Caria
- Anaia, Caria
- Bargylia, Caria
- Chalke, Islands off Rhodes
- Chersonesos, Caria
- Euhippe, Caria
- Euromos, Caria
- Halikarnassos
- Iasos, Caria
- Idyma, Caria
- Kamiros, Caria
- Karyanda, Caria
- Kaunos, Caria
- Keramos, Caria
- Knidos, Caria
- Kos, Islands off Caria
- Kranaos, Caria
- Latmos, Caria
- Mylasa
- Myndos, Karia
- Nisyros, Islands off Caria
- Orthosia, Caria
- Rhodes, Caria
- Stratonikeia, Caria
- Syangela, Caria
- Tabai, Karia
- Telos, Caria
- Uncertain mint
The Persians under commander Harpagos conquer the area around Idyma.
The historian Herodotus is born in Halikarnassos.
The tyrant Lygdamis II puts to death the poet Panyasis, which causes the historian Herodotus to leave Halikarnassos.
Iasos is governed by Amorges, a Persian who had achieved independence from Persia. Iasos is attacked by Spartans, who deliver Amorges to Tissaphernes and plunder the city.
The Spartan Lysander takes Iasos, kills all men of fighting age, sells the women and children into slavery, and levels the city.
Hekatomnos becomes king of Caria, then including Halikarnassos, under the Persian Empire.
Euromos participates in the rebellion of the Persian satrap Cyrus the Younger against his brother, King Artaxerxes II.
Eresos, Byzantion, Chios,Mytilene, Methymna, Rhodes, Thebes, Korkyra, Eretria, Kios, Samos, Naxos, Andros, Myrina (Lembos), Hephaistia, Imbros, and Thasos join the Second Athenian League, reaffirming its alliance with Athens in response to the growing threat of Persian interference and internal Greek conflicts.
Mausolos moves the capital of the Hekatomnid Satrapy from Mylasa to Halikarnassos.
355 BCE
350 BCE
Construction of the Mausoleum of Halikarnassos, one of the Seven Wonders of the World.
Death of Mausolos at Halikarnassos and reign of his sister Artemisia II.
Death of Artemisia II at Halikarnassos and reign of her brother Idreios.
Death of Idreios at Halikarnassos and reign of his wife and sister Ada.
Ada is usurped by her brother Pixodaros in Halikarnassos.
Alexander the Great besieges and eventually takes Halikarnassos, which is strongly defended by Memnon of Rhodes.
326 BCE
216 BCE
The Lyttian War is fought between an alliance led by Knossos and one led by Polyrhenion. On the side of Knossos were Rhodes, the Aetolian League, and Kydonia. On the side of Polyrhenion were Lyttos, Macedon, and the Achaian League.
Eleutherna triggers the Lyttian War by accusing Rhodes of murdering their leader Timarchos.
197 BCE
Treaty of Apamea. Euromos, and Abydos returned to the Kingdom of Pergamon.
Construction of the Temple of Zeus Lepsinos begins in Euromos.
A major earthquake destroys Rhodes. Funds for is rebuilding are given by Antoninus Pius.