400 BCE – Antipater is born in Paliura, Macedon. Demetrios, Odrysian reign begins. 

390 BCE – Autophradates is born. 

390-380 BCE – Polyperchon is born.  

382 BCE – Philip II is born. Antigonos I Monophthalmos is born. 

380 BCE – Memnon of Rhodes born in Rhodes. Darius III is born. 

371 BCE – Thebes defeats Sparta in Battle of Leuctra. Thebes is now dominant city state. 

317 BCE – Alexander I Molossos is born. 

370’s or 360’s BCE – Mazaios is born 

369 BCE – Alexander II ascends to Macedonian throne. 

368 BCE – Philip II sent to Thebes as part of agreement with Alexander II

367 BCE – Ptolemy I is born. Alexander II assassinated at festival by Ptolemy of Aloros. 

365 BCE – Spithridates is born. Perdikkas III becomes king of Macedon. 

364 BCE – Philip II returns to Macedon.  

361 BCE – Pumiathon takes throne of Kition. 

360 BCE – Thasian colonist found city of Krenides (later Philippi). Lysimachos is born in Pella.

360 BCE (September) – Kersebleptes inherits throne from father, Kotys I. Amatokos II inherits throne from Amatokos I. 

359 BCE – Philip II’s older brother Perdikkas III is killed in battle against Illyria, and he becomes king. Philip III is born. 

358 BCE – Seleukos I Nikator is born in Europos, Macedon. 

358 BCE – Memnon of Rhodes together with brother Mentor, join revolt of Artabazos II against Artaxerxes II. After losing, Memnon flees to Macedonia, where he became acquainted with Philip II and Alexander III

357 BCE – Philip II marries Olympias. Philip II conquers Amphipolis

356 BCE – Alexander of Pherae murdered by Teisiphon, sister Thebe, and brothers. 

356 BCE (20/21 of July) – Alexander the Great is born in Pella 

356 BCE – Philip II conquers town of Krenides and renames it to Philippi. Ketriporis begins reign in Thrace. 

355 BCE – Philip II loses an eye in the siege of Methone. 

355 BCE – Perdikkas is born. Kassander is born. Bucephalos is born. 

352 BCE – Philip II invades kingdom of Kersebleptes. Amatokos II disappears from records. His son, Teres II begins reign. 

351 BCE – Pnytagoras begins reign in Salamis. 

350 BCE (approximate) – Alexarchos is born. Ophellas is born. Presumed beginning of reign of Timarchos of Paphos

349 BCE – Olynthian war, which ended with Philip II conquering the Chalkidian League. Chares participates without success. 

347 BCE – Kersebleptes allies with Athens in Thrace, resulting in campaign by Philip II under Antipater

346 BCE – Philip II subdues Greek city states. Turns his attention east. 

344 BCE – Mazaios begins issuing coins at Sidon. Alexander wins bet with Philip II and receives Bucephalos

343 BCE – Philetairos born near the Black Sea. 

342 BCE – Antipater appointed by Philip II to be regent of Macedon. 

341 BCE – Kingdoms of Kersebleptes and Teres II overrun by Philip II

340 BCE – Antigonos loses an eye in the siege of Perinthos. Philip II begins the siege of Byzantion, which is ultimately unsuccessful. Chares is sent to aid Byzantion but is dismissed. 

340 BCE – Patraos becomes king of Paeonia. Pixodaros seizes Halicarnassos from sister Ada. 

340 BCE (approximately) – Chandragupta Maurya is born. Sabakes takes over administration of Egypt. Demetrios, Odrysian reign ends. 

339 BCE – Memnon of Rhodes helps defend Byzantion against Philip II

338 BCE – Philip II defeats Athens and Thebes at the Battle of Chaeronea. Aetolian League receives Naupactos from Philip II. Chares is sent to aid Amphissa but is unsuccessful. 

337 BCE – Alexander the Great briefly flees to Illyria when Philip II marries, but returns after about six months.  

337 BCE – Demetrios I Poliorketes is born. Dionysios becomes sole ruler of Herakleia Pontika. 

336 BCE (21 October)  – Philip II is assassinated at the wedding of Alexander I Molossos and Kleopatra of Macedon. Alexander the Great becomes king. Darius III reign begins. 

335 BCE – Alexander the Great puts down rebellions in Thrace, Thebes, and Athens, supported by the Aetolian League. Thebes is annihilated. Kalas defeated by Memnon of Rhodes

334 BCE – Antipater left as regent of Macedon and strategos of Europe. Alexander I Molossos crosses over to Italy at behest of Tarentum. 

334 BCE (May)  – Battle of the Granicus. First battle between Alexander the Great and Persia. Alexander is nearly killed by Spithridates before his arm is cut off by Kleitos the Black. Spithridates dies of his wounds Memnon of Rhodes participates on the Persian side. Kalas leads Thessalian cavalry and is given satrapy of Hellespontine Phrygia. 

334 BCE – Antigonos appointed satrap of Phrygia, responsible for protecting Alexander’s supply lines. Asandros appointed satrap of Lydia. Pixodaros dies. 

333 BCE – Memnon of Rhodes leads western satrapies, including Autophradates, against Alexander III. He captures Chios and Lesbos and encourages rebellions in Sparta and Athens. Memnon of Rhodes is killed in a siege at Mytilene. 

333 BCE – Alexander defeats Darius III at the battle of Issus. Sabakes is killed. 

333 BCE – Polyperchon given control over Tymphaean battalion of the phalanx. Menes promoted to king’s body guards. Balakros receives satrapy of Cilicia. 

333 BCE – Urimilk III surrenders Byblos to Alexander the Great. Straton surrenders Sidon. Gerostratosson surrenders Arados. 

332 BCE – Androkles of Amathos and Pnytagoras support Alexander the Great. Siege of Tyre under Azemilkos. Samaria initially submits to Alexander, then revolts and is destroyed. 

332 BCE – Alexander invades Egypt and founds city of Alexandria.  

332 BCE – Alexander I Molossos killed at the Battle of Pandosia. 

332/331 BCE – Archon wins horse races at the Isthmian Games and Pythian Games. 

331 BCE – Nikokreon visits Alexander at Tyre and pays homage to him. 

331 BCE – Alexander defeats Darius III again at the battle of Gaugamela. Mazaios leads right wing. 

331 BCE (October) – Mazaios surrenders Babylon to Alexander. Mazaios named as satrap of Babylon. Menes assigned government of Syria, Phoenicia, and Cilicia. Menander appointed to Lydia. Philoxenos appointed satrap in Asia Minor. 

330 BCE – Antipater defeats Sparta near Megalopolis. Alexander refers to it as a “battle of mice in Arcadia.” 

330 BCE – Autophradates surrenders to Alexander. Darius III is killed by his satrap Bessus. 

328 BCE – Mazaios dies. Stamenes takes over as satrap of Babylon. Asandros leads Greek mercenaries to join Alexander

327 BCE – Seleukos is in charge of the silver shields. Sophytes submits to Alexander the Great and gifts him several hunting dogs. 

326 BCE – Alexander wins the Battle of the Hydraspes over King Porus. Bucephalos dies. 

325 BCE – Seuthes III revolts against Macedon. Presumed passing of Paphos from Timarchos to Nikokles. 

325 BCE – Peithon, son of Agenor, commands a phalanx in the Mallian campaign. Named viceroy of the Indus area. Koinos named satrap of Susa. Demarchos given satrapy of Hellespontine Phrygia, replacing Kalas, who died. 

324 BCE – Susa weddings. Lysimachos crowned by Alexander for his achievements. Seleukos marries Apama, eventual mother of Antiochos I Soter

324 BCE – after death of Hephaestion, Perdikkas elevated to commander of the Companion Cavalry. Kleitos the White sent back to Macedonia with Krateros. 

324 BCE – Antiochos I Soter is born. 

323 BCE (10/11 of June) – Alexander dies from illness in Babylon. On his death bed, he gives his signet ring to Perdikkas

323 BCE –Lysimachos appointed strategos of Thrace where he fights Seuthes III to a draw. Antigonos put in charge of Phrygia, Lycaonia, Pamphylia, Lycia, and western Pisidia. Ptolemy put in charge of Egypt. Laomedon put in charge of Syria. Stamenes dies of natural causes. Asandros is given Caria. Menander removed from Lydia in favor of Kleitos the White and given charge of some of Antigonos’ forces against Eumenes. Antigenes is given Susiana. 

323/322 BCE – Alexander IV is born. 

322 BCE – Antipater defeats Athens, Aetolia, and Thessaly in the Lamian War with the help of Krateros and Polyperchon. Stasioikos II of Marion takes throne. 

322 BCE – Philip III marries Euridyce. Amastris marries Dionysos of Herakleia Pontika 

322 BCE – Perdikkas orders Antigonos I Monophthalmos to appear before court to answer why he failed to support the invasion of Cappadocia. Antigonos instead flees to Antipater. They both join in alliance with Ptolemy against Perdikkas

322 BCE – Chandragupta Maurya conquers Nanda empire. Laranda and Isaura Palaia destroyed by Perdikkas. Ophellas sent by Ptolemy I to subdue Kyrene. 

321 BCE – body of Alexander the Great is stolen by Ptolemy while on its way to Macedon. Perdikkas is enraged. 

321 BCE – Dokimos is assigned the satrapy of Babylon. When Archon refuses to cede it, he is killed in battle. Philoxenos given satrapy of Cilicia. At Triparidisos, Adea Eurydike attempts to take control of Macedonian army at expense of Antipater, Antigonos, and Seleukos.

321/320 BCE – after a disastrous attempt to cross the Nile to confront Ptolemy, Perdikkas is murdered by his generals Peithon, Antigenes, and Seleukos

320 BCE – Triparadisus accords. Antipater made new regent. Antigonos becomes stategos of Asia. Laomedon receives Syria. Seleukos is given Babylon. Asandros receives Caria. Koinos no longer mentioned. 

320 BCE – Antigonos II Gonatas born. 

320 BCE – Antipater dies. He leaves recency to Polyperchon, excluding Kassander

319 BCE – Laomedon defeated by Ptolemy and taken prisoner. 

319 BCE – Adea Eurydike takes control of Macedonia.

319 BCE – Ptolemy Keraunos is born. 

319/318 BCE – Pyrrhos of Epiros is born. 

318 BCE – Antigonos moves against Kleitos the White, who sails away to Polyperchon

317 BCE (December 25) – Philip III and Adea Eurydike executed by Olympias. 

317 BCE – Asandros expands into Lycia and Cappadocia and joins against Antigonos

317 BCE – Polyperchon defeated at Megalopolis by forces loyal to Kassander. Polyperchon’s fleet is destroyed by Antigonos. Kassander takes Athens. Kleitos the White initially defeats force sent by Kassander and Antigonos, then is caught by surprise and defeated by Antigonos. Kleitos the White escapes by boat, but is later killed by soldiers loyal to Lysimachos

316 BCE – Kassander defeats and murders Olympias, mother of Alexander and takes Alexander IV hostage. Polyperchon makes an alliance with Antigonos, and gives him the regency.

316 BCE – Peithon, son of Agenor, departs India for Babylon and is named satrap of Baylonia. Aspesias becomes satrap of Susiana. 

316 BCE – Arsinoe II is born. 

315 BCE – Antigonos finally defeats Eumenes after he’s betrayed. Against wishes of Demetrios, Antigonos executes Eumenes. Antigenes is thrown in a pit and burned alive. 

315 BCE – Antigonos arrives in Babylon and forces Seleukos to flee to Ptolemy in Egypt. 

315 BCE – Nikokreon allies with Ptolemy against Antigonos. Menelaus sent to subjugate Cyprus. Ptolemy rewards him with more territory in Cyprus. 

315 BCE – Uranopolis founded by Alexarchos

315 BCE – Patraos dies. 

314 BCE – Lysimachos, Ptolemy, Kassander, and Seleukos join against Antigonos. Eupolemos sent by Kassander to invade Caria. 

313 BCE – Pleistarchos left in charge of Chalcis against Ptolemy by Kassander

313 BCE – Seuthes III supports revolt in Kallatis against Lysimachos and is defeated but not conquered. 

312 BCE – Antigonos captures Lydia and Caria, driving Asandros out. Ptolemy defeats Demetrios at the Battle of Gaza. Peithon, son of Agenor, participates on the side of Demetrios and is killed. 

312 BCE – Stasioikos II of Marion and Pumiathon of Kition are killed and their cities are sacked by Menelaus under Ptolemy I

311 BCE – Alexander IV and his mother Roxana are murdered by Kassander. Peace treaty between Kassander/Ptolemy and Antigonos

310 BCE – War between Seleukos and Antigonos with Demetrios in Babylonian War, which eventually ended with Seleukos victorious. 

309 BCE – Lysimachos founds Lysimacheia 

309/308 BCE – Ptolemy II Philadelphos born on island of Kos. 

308 BCE – Kleopatra attempts to marry Ptolemy I, but is executed under orders of Antigonos. Ophellas is killed by Agathokles of Syracuse. 

307/305 BCE – Seleukos founds Seleukia. 

306 BCE – Demetrios defeats Ptolemy’s navy and Menelaus in Battle of Salamis. Dionysios of Herakleia Pontika dies. 

305 BCE – Seleukid-Mauryan war between Seleukos and Chandragupta begins. 

304 BCE – Demetrios leaves Rhodes after a failed year-long siege.  

304 BCE – Last mention of Polyperchon. His fate is unknown. 

303 BCE – Seleukos and Chandragupta agree on peace. Seleukos cedes eastern provinces to Chandragupta in exchange for 500 war elephants. Magas receives governorship of Kyrene. 

302 BCE – Second alliance of Lysimachos, Ptolemy, Kassander, and Seleukos against Antigonos made. Pleistarchos sent by Kassander to join with Lysimachos against Antigonos. Philetairos shifts allegiance from Antigonos to Lysimachos.  

302 BCE – Lysimachos marries Amastris. 

301 BCE – Lysimachos, Ptolemy, Kassander, and Seleukos defeat Antigonos and Demetrios. Antigonos is killed in battle. Lysimachos receives Lydia, Ionia, Phrygia, and north coast of Asia Minor. Kassander is undisputed ruler of Macedonia. Pleistarchos rewarded with Cilicia. Philetairos made commander of Pergamon by Lysimachos

301 BCE – Lysimachos marries Arsinoe II, daughter of Ptolemy to seal an alliance. 

301 BCE – Aetolian League gains control of Parnassos and Delphi. 

300 BCE – Seleukos founds Antioch. Amastris founds Amstris. 

300 BCE – Demetrios expels Pleistarchos from Cilicia. Pleistarchos is given rule in Caria. 

299 BCE – Ptolemy Epigonos is born. 

298 BCE – Chandragupta abdicates throne. 

298 BCE – Pyrrhos taken hostage in Alexandria due to a peace treaty between Ptolemy and Demetrios. Pyrrhos marries a stepdaughter of Ptolemy

297 BCE – Demetrios renews hostilities against Lysimachos

297 BCE – Kassander dies of dropsy. Philip IV takes throne, but dies himself of dropsy three months later. Pyrrhos returns to Epirus as co-ruler with aid of Ptolemy

295 BCE (approximate) – Chandragupta Maurya dies. 

294 BCE – Demetrios and Lysimachos make peace. Demetrios murders Alexander V and is recognized as ruler of Macedonia. 

293 BCE – Pleistarchos no longer rules over Caria. 

292 BCE – Agathokles taken prisoner by Getae king Dromichaetes, then released. 

292 BCE – Antiochos I elevated to co-ruler with Seleukos. Antiochos I marries Stratonice, daughter of Demetrios

292 BCE – Pyrrhos goes to war against Demetrios, but is forced to retreat. Pyrrhos second wife leaves him for Demetrios

290 BCE (approximate) – Alexarchos dies. 

289 BCE – Pyrrhos again invades Macedonia due to Demetrios illness. After Demetrios recovers, Pyrrhos is forced to retreat. 

287 BCE – Lysimachos with Agathokles and Pyrrhos drive Demetrios out of Macedonia, after he attempted to retake Delphi from the Aetolian League. Ptolemy Keraunos departs Egypt. Lysimachos executes Eurydike

286 BCE – Demetrios taken prisoner by Seleukos

285 BCE – Lysimachos expels Pyrrhos from Macedonia and rules himself. 

284 BCE – Ptolemy Keraunos and Arsinoe II scheme together to convince Lysimachos to put his eldest son Agathocles to death. 

284 BCE (28 March) – Ptolemy II declared king of Egypt. Amastris drowned by two sons. 

284-281 BCE – Ptolemy II marries Arsinoe I, daughter of Lysimachos.

283 BCE – Demetrios dies in prison. 

282 BCE – Ptolemy I dies. 

282 BCE – Philetairos deserts Lysimachos and offers Pergamon to Seleukos

282 BCE – Pyrrhos aids Tarentum in struggle against Rome. 

281 BCE – Lysimachos killed in Battle of Corupedium against Seleukos. Seleukos murdered by Ptolemy Keraunos during prayer. 

280 BCE – Ptolemy Keraunos marries half-sister Arsinoe II and murders her two youngest children. 

280 BCE – Ptolemy Keraunos fights a war against Illyria and maybe oldest son of Arsinoe II

280-279 BCE – Pyrrhos defeats Rome in two costly victories. 

278 BCE – Pyrrhos joins against Carthage in Sicily. Ptolemy Epigonos attempts to regain Macedonia without success. 

279 BCE (January/February) – Ptolemy Keraunos killed by Gauls. Gauls defeated by Aetolian League

278 BCE – Nikomedes I takes the throne of Bithynia. 

277 BCE – Antigonos Gonatas recognized as king of Macedon after defeating Gauls

276 BCE – Magas becomes king of Kyrene. 

275 BCE – Gaul invasion of Anatolia stopped by Antiochos, using war elephants. Earns his title “Soter”. 

274 BCE – Ptolemy II declares war on Antiochos I and invades Syria. Ptolemy II is defeated and is forced to retreat. 

273/272 BCE – Ptolemy II marries Arsinoe II, his sister. 

272 BCE – In Battle of Argos, with Argos supported by Antigonos Gonatas, Pyrrhos is killed by a brick from an old woman. 

271 BCE – Due to economic issues and plague, Antiochos I abandons war against Ptolemy II

270-260 BCE – Arsinoe II dies. 

264 BCE – Nikomedes I founds Nikomedia. 

263 BCE – Philetairos dies and leaves Pergamon to his nephew, Eumenes I. 

262 – 255 BCE – Ptolemy II and Antigonos II engage in naval war over Aegean. Antigonos II defeats his forces at Battle of Kos, ending Ptolemaic supremacy over the Aegean. 

261 BCE – Antiochos I dies. 

260 BCE – War breaks out again between Ptolemy II and Antiochos I

258 BCE – Ptolemy Epigonos put in charge of Telmessos. 

255 BCE – Nikomedes I dies. 

253 BCE – Ptolemy II and Antiochos I negotiate peace treaty. Ptolemy II cedes land to Antiochos I. Antiochos I marries Ptolemy II’s daughter. 

250 BCE – Magas dies. 

246 BCE (28 January) – Ptolemy II dies. 

240 BCE – Ptolemy Epigonos dies. 

229 BCE – Antigonos Gonatas dies.