Cyclades
- Anaphe, Cyclades
- Andros, Cyclades
- Astypalaia
- Delos, Cyclades
- Ioulis, Keos, Cyclades
- Karthaia, Keos, Cyclades
- Kea, Cyclades
- Koressos, Keos, Cyclades
- Kythnos, Cyclades
- Melos, Cyclades
- Naxos, Cyclades
- Paros, Cyclades
- Syros, Cyclades
- Tenos, Cyclades
The Persian admiral Datis stops at Delos to pay his respects and demonstrate to the Greeks that the Persians are not hostile to their gods.
The satrap of Phrygia, Pharnakes, offers asylum in Adramytteion to exiles from Delos.
Eresos, Byzantion, Chios,Mytilene, Methymna, Rhodes, Thebes, Korkyra, Eretria, Kios, Samos, Naxos, Andros, Myrina (Lembos), Hephaistia, Imbros, and Thasos join the Second Athenian League, reaffirming its alliance with Athens in response to the growing threat of Persian interference and internal Greek conflicts.
With Theban power down after the death of Epaminondas, Alexander of Pherai takes Tinos and sells the inhabitants as slaves, then besieges Peparethos. Athens defeats Alexander near Sounion and relieves Peparethos. Alexander then plunders Piraios.
Antigonos I Monophthalmos Declaration of Tyre grants autonomy to all Greek cities. While its effects weren’t the same everywhere, it allowed Delos to regain control of its Temple to Apollo from Athens.
Antigonos Monophthalmos creates the Koinon of the Nesiotes, the first federation of the Cyclades Islands, with Delos as its common sanctuary.
Mithridates VI‘s troops take Delos and ransack it.
Delos destroyed again by pirates under Athenodoros, an ally of Mithridates VI.