Soloi was extremely important during ancient times due to its proximity to the Cilician Gates. Pretty much every conqueror in history who wanted to get to or from Syria needed to get through them. This included Alexander the Great. To top it off, Soloi had an important harbor.
During Xenophon’s time, the area was ruled by Tiribazos. By Alexander the Great’s time, it was ruled by Balakros, who was against him in the Battle of Issos but later went over to him and became one of his most trusted satraps.
However, the city itself supported the Persians when Alexander arrived, so he imposed a hefty fine on it. After his death, the city came under the control of Ptolemy I Soter, though Demetrios I Poliorketes tried unsuccessfully to take it. After that, it moved between different diadochi – usually between the Ptolemies and the Seleukids. Being such a key location, no ruler could leave it alone.
Alexander the Great conquers Cilicia, including Aigai.Tarsos (where he became ill after a swim in the Kydnos River), Soloi, Issos, and Mallos, where he made sacrifices.
Following the victory in the Battle of Ipsos, Cilicia comes under Seleukid control with Seleukos I Nikator. This included Aigai.Tarsos, Soloi, Issos, and Mallos.