106 CE
Adramytteion severely damaged during an earthquake. Trajan provides funds to rebuild it.
115 CE
While being visited by the Emperor Trajan, Antioch is severely damaged in an earthquake. The same earthquake heavily damages Apameia on the Axios.
115 CE
Roman Emperor Trajan briefly occupies Babylon during his campaign against the Parthian Empire.
116 CE
During Emperor Trajan’s Parthian campaign, Adiabene is briefly occupied by Roman forces as part of their conquest of Mesopotamia.
117 CE
Pliny the Younger, serving as the Roman governor of Bithynia et Pontus, writes to Emperor Trajan about various administrative matters in the province, including Amastris.